Comorbidity of Diabetes and Covid-19 in 570 Positive Polymerase Chain Reaction Patients in Yazd-2019-2020

Authors

  • Kazem Ansari MD, Nano-Biotech Foresight Company Biotechnology Campus, Yazd Stem Cells and Regenerative Medicine Institute, Yazd, Iran.
  • Mohammad Cheraghipour MD, Islamic Azad University of Yazd, Yazd, Iran.
  • Seyed Alireza Mousavi Assistant Professor, Infectious Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Zohreh AkhoundiMeybodi Assistant Professor of Prevention and Control of Nosocomial Infection, Infectious Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Abstract:

Objective: Epidemiological evidence shows that the prevalence of patients with comorbidity of diabetes mellitus (DM), in Coronavirus disease 2019 (COVID-19) is remarkable and they have poor prognosis. We aimed to investigate the comorbidity of diabetes and covid-19 in positive Polymerase Chain Reaction people in Yazd. Materials and Methods: This retrospective cohort study included data of 570 COVID-19 positive patients, admitted to Shahid Sadoughi Hospital in Yazd, Iran, from February2019 to May 2020, including demographic data and clinical outcome of COVID-19. Study data were analyzed using SPSS software-22 and T-test, Chi-square and a binary logistic regression model were used for modeling. Results: Prevalence of COVID-19 patients with diabetes was 27% and the percentage of male patients was 62.6%. Additionally, duration of hospitalization significantly higher in diabetic patients (P= 0.004), need to invasive mechanical ventilation in diabetic patients was significantly higher than non-diabetic patients (P˂ 0.001) Conclusion: DM is one of the most important comorbidity with COVID-19 patients and this comorbidity affects the severity of the disease and the outcome of patients.  

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Journal title

volume 14  issue 3

pages  138- 144

publication date 2022-09

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